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BioHelix announced today that
it has entered into a licensing agreement with Harvard University
for exclusive, worldwide rights to commercialize a novel Whole
Genome Amplification (WGA) technology developed at Harvard Medical
School. WGA techniques are typically used to amplify genomic DNA
for archiving and downstream analysis including genotyping, forensics,
comparative genomic hybridization, and single cell analysis. The
Harvard invention mimics the DNA replication process found in nature
in that it uses an enzyme called primase to synthesize primers on-site,
generating multiple initiation sites for random, whole genome amplification.
There are several competitive advantages to Harvard's rapid, primase-based
WGA (pWGA) technology. In particular, Harvard's pWGA is significantly
faster than all other commercially available WGA techniques. The
reaction time for pWGA is less than one hour. This makes it a much
more attractive technology for use in diagnostic applications than
other conventional methods.
"Nucleic acid testing in molecular
diagnostics is a rapidly growing field," said Dr. Huimin Kong, President
and CEO of BioHelix. "BioHelix is developing a rich portfolio of
technology platforms for nucleic acid analysis and molecular diagnostics
and Harvard's pWGA technology fits very well into our product development
pipeline. BioHelix aims to develop and commercialize novel pWGA-based
products for life science research, DNA detection, and clinical
diagnostics. "
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